Articles

EinNext Biosciences at CPHI & PMEC India 2024

Rosita Mary - Research Associate

The EinNext team, comprising Mr. Albert Einstein, Ms. Rosita, and Ms. Christy Diana, along with our partners at BIOVIA, recently attended CPHI & PMEC India 2024, a premier event in the pharmaceutical industry.Held from November 26th to 28th, 2024, at the India Expo Centre in Greater Noida, the event served as a valuable platform for networking, learning, and exploring the latest industry trends.

With over 1,500 exhibitors, the event featured a wide range of pharmaceutical manufacturers, ingredient suppliers, equipment providers, contract research organizations, and regulatory consultants. Many showcased their products and technologies through live demonstrations, offering attendees a deeper understanding of industry innovations.

Conference sessions covered a variety of topics, including API development, formulation challenges, regulatory compliance, and digital transformation. Industry experts shared their knowledge through presentations and panel discussions.

Our team actively participated in sessions, visited booths, and engaged in discussions, gaining valuable insights into the evolving pharmaceutical landscape. We were particularly impressed by the focus on innovation, sustainability, and digitalization, which we look forward to leveraging for future growth at EinNext.

EinNext hopes to continue building on the connections made at CPHI & PMEC India 2024 and explore new opportunities to drive innovation and excellence in the pharmaceutical industry.

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Model-Based Systems Engineering (MBSE) Approach for Digital Twin Integration in Industrial Automation to Enhance OEE

Dr. Paul Sathiyan - Director, Automotive Power Electronic Drives, AIoT, MBSE

As industries embrace digital transformation, Digital Twin technology has emerged as a powerful tool for simulating, monitoring, and optimizing systems across their lifecycle. MBSE emphasizes the use of formalized models to manage system requirements architecture, design, and analysis. The integration of Model-Based Systems Engineering (MBSE) with Digital Twin technology in industrial automation is revolutionizing the way systems are designed, managed, and improved.

By leveraging this combination, organizations can significantly increase Overall Equipment Effectiveness (OEE), ensuring optimal performance, availability, quality, and reduce downtime with Predictive Maintenance.

Key Aspects of MBSE-Driven Digital Twin Integration

MBSE-driven Digital Twin integration encompasses system modeling and simulation, where MBSE defines the structural, functional, and behavioral aspects of manufacturing systems using tools like SysML, MATLAB Simulink, or Cameo Systems Modeler to form the foundation for Digital Twins.

Real-time data from IoT sensors and PLCs (Programmable Logic Controllers) is mapped to MBSE models for accurate synchronization between the physical and digital systems, ensuring seamless data connectivity and integration. Lifecycle management ensures Digital Twins remain aligned with the evolving requirements of industrial assets from design to decommissioning.

Continuous closed-loop feedback between physical systems and their Digital Twins facilitates real[1]time updates to MBSE models, driving operational excellence. Lastly, performance optimization leverages these MBSE-driven Digital Twins to simulate scenarios, optimize machine performance, reduce cycle times, and eliminate bottlenecks.

Benefits of MBSE-Driven Digital Twin Integration for OEE

By increasing equipment availability through predictive maintenance, Digital Twins and MBSE reduce unplanned downtime by identifying potential failures before they occur. Real[1]time data integration enables Digital Twins to optimize machine performance, improving throughput and reducing cycle times, thereby enhancing performance efficiency.

Improved product quality is achieved as MBSE models simulate and validate production processes, addressing quality issues proactively. Virtual commissioning and design validation facilitated by this integration shorten the time required to deploy new systems, reducing time-to[1]market and accelerating production ramp-up. Additionally, cost savings are realized by detecting inefficiencies early and minimizing downtime, helping manufacturers achieve significant financial benefits.

Challenges in MBSE and Digital Twin Integration for Industrial Automation

MBSE and Digital Twin integration face challenges including the vast volume and complexity of data generated by industrial automation systems, requiring robust frameworks and tools for effective integration with MBSE models. Tool interoperability is essential to ensure compatibility between MBSE tools, Digital Twin platforms, and industrial automation systems for seamless operation.

The integration process demands skilled expertise in MBSE methodologies, Digital Twin technology, and industrial automation, necessitating significant training investments. Scalability remains a hurdle as developing scalable solutions for complex industrial systems with multiple interdependencies poses substantial difficulties. Additionally, real-time data exchange between physical systems and Digital Twins introduces cybersecurity concerns, necessitating robust measures to mitigate potential risks.

Challenges in MBSE and Digital Twin Integration for Industrial Automation

MDoX by EinNel Technologies address these challenges by leveraging advanced data processing frameworks to manage the complexity and volume of data generated in industrial automation systems.

EinNel Technologies combines domain expertise in MBSE methodologies, Digital Twin technology, and industrial automation to create scalable, interoperable solutions tailored to client needs.  With MDoX, seamless integration between MBSE models and industrial systems is achieved, ensuring compatibility across tools and platforms. Their robust security protocols mitigate cybersecurity risks, while their continuous training programs ensure teams remain proficient in evolving technologies. This comprehensive approach ensures smooth implementation and maximized benefits from MBSE and Digital Twin integrations.

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AI-Powered LIMS: Transforming the Labs Smarter

Rosita Mary - Research Associate

In today’s fast-paced scientific landscape, laboratories face increasing pressure to deliver accurate results while improving productivity. Traditional Laboratory Information Management Systems (LIMS), though foundational, struggle to keep up with the complexity automation to create scalable, interoperable solutions tailored to client needs. With MDoX, seamless integration between MBSE models and industrial systems is achieved, ensuring compatibility across tools and platforms.

Their robust security protocols mitigate cybersecurity risks, while their continuous training programs ensure teams of modern scientific workflows, particularly in handling unstructured data and enabling real-time decision-making. AI-powered LIMS addresses these limitations by automating data analysis, ensuring consistency, and facilitating dynamic, data-driven decisions.

From high-throughput experiments in R&D to real-time quality control in manufacturing, AI-driven systems streamline processes, enhance regulatory compliance, and significantly reduce manual intervention, saving both time and resources. By integrating AI, laboratories can achieve unprecedented operational efficiency and innovation.

AI-powered LIMS enables seamless collaboration between teams, predictive analytics for proactive issue resolution, and faster, more informed decision-making. This transformative technology positions laboratories to meet growing demands for faster drug development and personalized treatments while maintaining precision and reliability.Organizations adopting AI-driven LIMS today are not just improving their current workflows—they’re future-proofing their labs to lead in the rapidly advancing life sciences landscape.

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An overview of a Warehouse Digital Twin

Albert Einstein - Founder & CEO

A Warehouse Digital Twin is a realtime, data-driven virtual replica of a warehouse, representing its assets, processes, and systems with high fidelity. It serves as a digital counterpart to real-world operations, leveraging advanced AI capabilities for perception, reasoning, and decision-making to optimize warehouse activities. By integrating real-time data from Internet of Things (IoT) devices, Warehouse Management Systems (WMS), and other sources, a warehouse digital twin dynamically estimates operational behaviour. It enables performance prediction of key performance indicators (KPIs), demand forecasting, and inventory optimization. This real-time simulation allows businesses to track and improve efficiency with greater precision.

One of the key advantages of building a warehouse digital twin is its ability to conduct virtual system testing. Businesses can simulate layout changes, software upgrades, or process optimizations and measure the anticipated performance improvements before implementing changes in the physical environment. This mitigates the risk of system downtime or performance degradation, ensuring smoother transitions. EinNel Technologies offers engineering and technology to the automotive manufacturing sector, helping companies implement Warehouse Digital Twin applications. These solutions enable businesses to overcome common challenges such as inventory and location accuracy, overstock issues, supply chain disruptions, space utilization, material flow control, labour management, and demand forecasting, thus driving better operational efficiency and business outcomes.

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Embrace, Evolve, Elevate: A Story of Transformation

Nagendra Kumar - Director, Engineering

In the world of automotive engineering, the car body is often a blend of different metals, with steel traditionally taking the lead and aluminium playing a smaller role. Recognizing aluminium’s unique qualities, researchers envisioned a greater role for it in the automotive industry. To explore its potential, they worked tirelessly to develop new technologies and reimagine aluminium’s place in car manufacturing. To illustrate this journey, let’s imagine a candid conversation between aluminium and a car manufacturer to understand why aluminium wasn’t being utilized more. In this fictional dialogue, we follow a story of discovery, innovation, and transformation as researchers push the boundaries of what aluminium can achieve in the automotive industry. It’s a tale of how new perspectives can drive the automotive industry toward a lighter, greener, and more efficient future.

Aluminium: “Hey! I’ve noticed that steel is used a lot more than me in car bodies. I’m a good metal too, you know! Why do you prefer steel over me?”

Car Manufacturer: “Well, Aluminium, steel is strong, and we can easily form it into thin sheets. Plus, it can be welded seamlessly. Do you have those qualities?” (Aluminium leaves, feeling disappointed but determined)

Aluminium: (thinking) “I may not be steel, but I have my strengths too. I’m lighter, which could improve fuel efficiency... Maybe I should try again.” (Aluminium returns to the manufacturer with newfound confidence)

Aluminium: “I’ve been thinking. I may not have all of steel’s qualities, but I am lighter. If you use me more, your cars could be more fuel-efficient. What do you think?”

Car Manufacturer: “That’s a good point, Aluminium, but the thing is, you still can’t be formed into thin sheets or welded as efficiently as steel. Those are big challenges.” (Despite the setback, Aluminium doesn’t lose hope. Instead, it starts researching and exploring new technologies.)

Aluminium: “(excitedly) Wait, what’s this? Giga Casting? This could change everything!” Armed with this new knowledge, aluminium approached the manufacturer once more, demonstrating the advantages of Giga Casting and how it could transform the manufacturing process. And the rest is history. Through this journey, aluminium teaches us valuable lessons:

Embrace the Change Mindset: Despite its aspirations, aluminium couldn’t change its situation until it accepted the need for transformation. Once it embraced this mindset, it began discovering new solutions.

Evolve Through Transformation: The journey was not easy. Aluminium had to endure extreme conditions—melting at 1000°C, being poured into molds, and undergoing rigorous quality testing. This phase required patience and trust in the process, even when the outcome was uncertain. Elevate Your Value: By adopting new technologies and processes, aluminium elevated its value in the eyes of the manufacturer, proving itself as a viable alternative to steel.

The story of aluminium reminds us that when faced with inevitable change, we should embrace it, evolve through transformation, and elevate our value. This mindset can lead to a more fulfilling and successful life, both personally and professionally.

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